Addition of a sequence from α(2)-antiplasmin transforms human serum albumin into a blood clot component that speeds clot lysis

BACKGROUND: The plasma protein α(2)-antiplasmin (α(2)AP) is cross-linked to fibrin in blood clots by the transglutaminase factor XIIIa, and in that location retards clot lysis. Competition for this effect could be clinically useful in patients with thrombosis. We hypothesized that fusion of N-termin...

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Detalles Bibliográficos
Autores principales: Sheffield, William P, Eltringham-Smith, Louise J, Gataiance, Sharon, Bhakta, Varsha
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654442/
https://www.ncbi.nlm.nih.gov/pubmed/19257897
http://dx.doi.org/10.1186/1472-6750-9-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654442/
https://www.ncbi.nlm.nih.gov/pubmed/19257897
http://dx.doi.org/10.1186/1472-6750-9-15

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