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Addition of a sequence from α(2)-antiplasmin transforms human serum albumin into a blood clot component that speeds clot lysis
BACKGROUND: The plasma protein α(2)-antiplasmin (α(2)AP) is cross-linked to fibrin in blood clots by the transglutaminase factor XIIIa, and in that location retards clot lysis. Competition for this effect could be clinically useful in patients with thrombosis. We hypothesized that fusion of N-termin...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654442/ https://www.ncbi.nlm.nih.gov/pubmed/19257897 http://dx.doi.org/10.1186/1472-6750-9-15 |