Genetic correction of splice site mutation in purified and enriched myoblasts isolated from mdx(5cv )mice

BACKGROUND: Duchenne Muscular Dystrophy (DMD) is an X-linked genetic disorder that results in the production of a dysfunctional form of the protein, dystrophin. The mdx(5cv )mouse is a model of DMD in which a point mutation in exon 10 of the dystrophin gene creates an artificial splice site. As a re...

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Detalles Bibliográficos
Autores principales: Maguire, Katie, Suzuki, Takayuki, DiMatteo, Darlise, Parekh-Olmedo, Hetal, Kmiec, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654480/
https://www.ncbi.nlm.nih.gov/pubmed/19236710
http://dx.doi.org/10.1186/1471-2199-10-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654480/
https://www.ncbi.nlm.nih.gov/pubmed/19236710
http://dx.doi.org/10.1186/1471-2199-10-15

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