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Genetic correction of splice site mutation in purified and enriched myoblasts isolated from mdx(5cv )mice
BACKGROUND: Duchenne Muscular Dystrophy (DMD) is an X-linked genetic disorder that results in the production of a dysfunctional form of the protein, dystrophin. The mdx(5cv )mouse is a model of DMD in which a point mutation in exon 10 of the dystrophin gene creates an artificial splice site. As a re...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654480/ https://www.ncbi.nlm.nih.gov/pubmed/19236710 http://dx.doi.org/10.1186/1471-2199-10-15 |