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Investigation of reproducibility of differentially expressed genes in DNA microarrays through statistical simulation

Recent publications have raised concerns about the reliability of microarray technology because of the lack of reproducibility of differentially expressed genes (DEGs) from highly similar studies across laboratories and platforms. The rat toxicogenomics study of the MicroArray Quality Control (MAQC)...

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Detalles Bibliográficos
Autores principales: Fan, Xiaohui, Shi, Leming, Fang, Hong, Harris, Stephen, Perkins, Roger, Tong, Weida
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654487/
https://www.ncbi.nlm.nih.gov/pubmed/19278560