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β-Lactam Resistance Response Triggered by Inactivation of a Nonessential Penicillin-Binding Protein

It has long been recognized that the modification of penicillin-binding proteins (PBPs) to reduce their affinity for β-lactams is an important mechanism (target modification) by which Gram-positive cocci acquire antibiotic resistance. Among Gram-negative rods (GNR), however, this mechanism has been...

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Detalles Bibliográficos
Autores principales: Moya, Bartolomé, Dötsch, Andreas, Juan, Carlos, Blázquez, Jesús, Zamorano, Laura, Haussler, Susanne, Oliver, Antonio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654508/
https://www.ncbi.nlm.nih.gov/pubmed/19325877
http://dx.doi.org/10.1371/journal.ppat.1000353