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β-Lactam Resistance Response Triggered by Inactivation of a Nonessential Penicillin-Binding Protein
It has long been recognized that the modification of penicillin-binding proteins (PBPs) to reduce their affinity for β-lactams is an important mechanism (target modification) by which Gram-positive cocci acquire antibiotic resistance. Among Gram-negative rods (GNR), however, this mechanism has been...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654508/ https://www.ncbi.nlm.nih.gov/pubmed/19325877 http://dx.doi.org/10.1371/journal.ppat.1000353 |