Better estimation of protein-DNA interaction parameters improve prediction of functional sites

BACKGROUND: Characterizing transcription factor binding motifs is a common bioinformatics task. For transcription factors with variable binding sites, we need to get many suboptimal binding sites in our training dataset to get accurate estimates of free energy penalties for deviating from the consen...

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Detalles Bibliográficos
Autores principales: Nagaraj, Vijayalakshmi H, O'Flanagan, Ruadhan A, Sengupta, Anirvan M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654563/
https://www.ncbi.nlm.nih.gov/pubmed/19105805
http://dx.doi.org/10.1186/1472-6750-8-94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654563/
https://www.ncbi.nlm.nih.gov/pubmed/19105805
http://dx.doi.org/10.1186/1472-6750-8-94

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