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De-Novo Identification of PPARγ/RXR Binding Sites and Direct Targets during Adipogenesis

BACKGROUND: The pathophysiology of obesity and type 2 diabetes mellitus is associated with abnormalities in endocrine signaling in adipose tissue and one of the key signaling affectors operative in these disorders is the nuclear hormone transcription factor peroxisome proliferator-activated receptor...

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Detalles Bibliográficos
Autores principales: Hamza, Mohamed Sabry, Pott, Sebastian, Vega, Vinsensius B., Thomsen, Jane S., Kandhadayar, Gopalan Srinivasan, Ng, Patrick Wei Pern, Chiu, Kuo Ping, Pettersson, Sven, Wei, Chia Lin, Ruan, Yijun, Liu, Edison T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654672/
https://www.ncbi.nlm.nih.gov/pubmed/19300518
http://dx.doi.org/10.1371/journal.pone.0004907