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De-Novo Identification of PPARγ/RXR Binding Sites and Direct Targets during Adipogenesis
BACKGROUND: The pathophysiology of obesity and type 2 diabetes mellitus is associated with abnormalities in endocrine signaling in adipose tissue and one of the key signaling affectors operative in these disorders is the nuclear hormone transcription factor peroxisome proliferator-activated receptor...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654672/ https://www.ncbi.nlm.nih.gov/pubmed/19300518 http://dx.doi.org/10.1371/journal.pone.0004907 |