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An Amphipathic α-Helix Controls Multiple Roles of Brome Mosaic Virus Protein 1a in RNA Replication Complex Assembly and Function

Brome mosaic virus (BMV) protein 1a has multiple key roles in viral RNA replication. 1a localizes to perinuclear endoplasmic reticulum (ER) membranes as a peripheral membrane protein, induces ER membrane invaginations in which RNA replication complexes form, and recruits and stabilizes BMV 2a polyme...

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Detalles Bibliográficos
Autores principales: Liu, Ling, Westler, William M., den Boon, Johan A., Wang, Xiaofeng, Diaz, Arturo, Steinberg, H. Adam, Ahlquist, Paul
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654722/
https://www.ncbi.nlm.nih.gov/pubmed/19325881
http://dx.doi.org/10.1371/journal.ppat.1000351