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An Amphipathic α-Helix Controls Multiple Roles of Brome Mosaic Virus Protein 1a in RNA Replication Complex Assembly and Function
Brome mosaic virus (BMV) protein 1a has multiple key roles in viral RNA replication. 1a localizes to perinuclear endoplasmic reticulum (ER) membranes as a peripheral membrane protein, induces ER membrane invaginations in which RNA replication complexes form, and recruits and stabilizes BMV 2a polyme...
Autores principales: | Liu, Ling, Westler, William M., den Boon, Johan A., Wang, Xiaofeng, Diaz, Arturo, Steinberg, H. Adam, Ahlquist, Paul |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654722/ https://www.ncbi.nlm.nih.gov/pubmed/19325881 http://dx.doi.org/10.1371/journal.ppat.1000351 |
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