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Methylation-Dependent Binding of the Epstein-Barr Virus BZLF1 Protein to Viral Promoters

The switch between latent and lytic Epstein-Barr virus (EBV) infection is mediated by the viral immediate-early (IE) protein, BZLF1 (Z). Z, a homologue of c-jun that binds to AP1-like motifs (ZREs), induces expression of the BRLF1 (R) and BRRF1 (Na) viral proteins, which cooperatively activate trans...

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Detalles Bibliográficos
Autores principales: Dickerson, Sarah J., Xing, Yongna, Robinson, Amanda R., Seaman, William T., Gruffat, Henri, Kenney, Shannon C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654727/
https://www.ncbi.nlm.nih.gov/pubmed/19325883
http://dx.doi.org/10.1371/journal.ppat.1000356