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Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield

BACKGROUND: The production of high yields of recombinant proteins is an enduring bottleneck in the post-genomic sciences that has yet to be addressed in a truly rational manner. Typically eukaryotic protein production experiments have relied on varying expression construct cassettes such as promoter...

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Detalles Bibliográficos
Autores principales: Bonander, Nicklas, Darby, Richard AJ, Grgic, Ljuban, Bora, Nagamani, Wen, Jikai, Brogna, Saverio, Poyner, David R, O'Neill, Michael AA, Bill, Roslyn M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654770/
https://www.ncbi.nlm.nih.gov/pubmed/19178690
http://dx.doi.org/10.1186/1475-2859-8-10