Paracrine sonic hedgehog signalling by prostate cancer cells induces osteoblast differentiation

BACKGROUND: Sonic hedgehog (Shh) and components of its signalling pathway have been identified in human prostate carcinoma and increased levels of their expression appear to correlate with disease progression and metastasis. The mechanism through which Shh signalling could promote metastasis in bone...

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Detalles Bibliográficos
Autores principales: Zunich, Samantha M, Douglas, Taneka, Valdovinos, Maria, Chang, Tiffany, Bushman, Wade, Walterhouse, David, Iannaccone, Philip, Lamm, Marilyn LG
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654862/
https://www.ncbi.nlm.nih.gov/pubmed/19254376
http://dx.doi.org/10.1186/1476-4598-8-12