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Paracrine sonic hedgehog signalling by prostate cancer cells induces osteoblast differentiation
BACKGROUND: Sonic hedgehog (Shh) and components of its signalling pathway have been identified in human prostate carcinoma and increased levels of their expression appear to correlate with disease progression and metastasis. The mechanism through which Shh signalling could promote metastasis in bone...
Autores principales: | Zunich, Samantha M, Douglas, Taneka, Valdovinos, Maria, Chang, Tiffany, Bushman, Wade, Walterhouse, David, Iannaccone, Philip, Lamm, Marilyn LG |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654862/ https://www.ncbi.nlm.nih.gov/pubmed/19254376 http://dx.doi.org/10.1186/1476-4598-8-12 |
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