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Comparison of methods for estimating the nucleotide substitution matrix

BACKGROUND: The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different mathematical bases. These methods include counting sequence differences and taking the log of the resulting probability matri...

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Detalles Bibliográficos
Autores principales: Oscamou, Maribeth, McDonald, Daniel, Yap, Von Bing, Huttley, Gavin A, Lladser, Manuel E, Knight, Rob
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655096/
https://www.ncbi.nlm.nih.gov/pubmed/19046431
http://dx.doi.org/10.1186/1471-2105-9-511