Domain duplication, divergence, and loss events in vertebrate Msx paralogs reveal phylogenomically informed disease markers

BACKGROUND: Msx originated early in animal evolution and is implicated in human genetic disorders. To reconstruct the functional evolution of Msx and inform the study of human mutations, we analyzed the phylogeny and synteny of 46 metazoan Msx proteins and tracked the duplication, diversification an...

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Detalles Bibliográficos
Autores principales: Finnerty, John R, Mazza, Maureen E, Jezewski, Peter A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655272/
https://www.ncbi.nlm.nih.gov/pubmed/19154605
http://dx.doi.org/10.1186/1471-2148-9-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655272/
https://www.ncbi.nlm.nih.gov/pubmed/19154605
http://dx.doi.org/10.1186/1471-2148-9-18

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