A Conserved Mechanism for Control of Human and Mouse Embryonic Stem Cell Pluripotency and Differentiation by Shp2 Tyrosine Phosphatase

Recent studies have suggested distinctive biological properties and signaling mechanisms between human and mouse embryonic stem cells (hESCs and mESCs). Herein we report that Shp2, a protein tyrosine phosphatase with two SH2 domains, has a conserved role in orchestration of intracellular signaling c...

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Detalles Bibliográficos
Autores principales: Wu, Dongmei, Pang, Yuhong, Ke, Yuehai, Yu, Jianxiu, He, Zhao, Tautz, Lutz, Mustelin, Tomas, Ding, Sheng, Huang, Ziwei, Feng, Gen-Sheng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655646/
https://www.ncbi.nlm.nih.gov/pubmed/19290061
http://dx.doi.org/10.1371/journal.pone.0004914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655646/
https://www.ncbi.nlm.nih.gov/pubmed/19290061
http://dx.doi.org/10.1371/journal.pone.0004914

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