RAD50 and NBS1 form a stable complex functional in DNA binding and tethering

The RAD50/MRE11/NBS1 protein complex (RMN) plays an essential role during the early steps of DNA double-strand break (DSB) repair by homologous recombination. Previous data suggest that one important role for RMN in DSB repair is to provide a link between DNA ends. The striking architecture of the c...

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Detalles Bibliográficos
Autores principales: van der Linden, Eddy, Sanchez, Humberto, Kinoshita, Eri, Kanaar, Roland, Wyman, Claire
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655673/
https://www.ncbi.nlm.nih.gov/pubmed/19151086
http://dx.doi.org/10.1093/nar/gkn1072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655673/
https://www.ncbi.nlm.nih.gov/pubmed/19151086
http://dx.doi.org/10.1093/nar/gkn1072

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