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RAD50 and NBS1 form a stable complex functional in DNA binding and tethering

The RAD50/MRE11/NBS1 protein complex (RMN) plays an essential role during the early steps of DNA double-strand break (DSB) repair by homologous recombination. Previous data suggest that one important role for RMN in DSB repair is to provide a link between DNA ends. The striking architecture of the c...

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Detalles Bibliográficos
Autores principales:	van der Linden, Eddy, Sanchez, Humberto, Kinoshita, Eri, Kanaar, Roland, Wyman, Claire
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655673/ https://www.ncbi.nlm.nih.gov/pubmed/19151086 http://dx.doi.org/10.1093/nar/gkn1072

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