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Chromatin remodeling finds its place in the DNA double-strand break response

The accurate repair of chromosomal double-strand breaks (DSBs) arising from exposure to exogenous agents, such as ionizing radiation (IR) and radiomimetic drugs is crucial in maintaining genomic integrity, cellular viability and the prevention of tumorigenesis. Eukaryotic cells have evolved efficien...

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Detalles Bibliográficos
Autores principales: Pandita, Tej K., Richardson, Christine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655678/
https://www.ncbi.nlm.nih.gov/pubmed/19139074
http://dx.doi.org/10.1093/nar/gkn1071