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Chromatin remodeling finds its place in the DNA double-strand break response
The accurate repair of chromosomal double-strand breaks (DSBs) arising from exposure to exogenous agents, such as ionizing radiation (IR) and radiomimetic drugs is crucial in maintaining genomic integrity, cellular viability and the prevention of tumorigenesis. Eukaryotic cells have evolved efficien...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655678/ https://www.ncbi.nlm.nih.gov/pubmed/19139074 http://dx.doi.org/10.1093/nar/gkn1071 |