Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK

Short-patch repair of DNA single-strand breaks and gaps (SSB) is coordinated by XRCC1, a scaffold protein that recruits the DNA polymerase and DNA ligase required for filling and sealing the damaged strand. XRCC1 can also recruit end-processing enzymes, such as PNK (polynucleotide kinase 3′-phosphat...

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Detalles Bibliográficos
Autores principales: Ali, Ammar A. E., Jukes, Rachel M., Pearl, Laurence H., Oliver, Antony W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655680/
https://www.ncbi.nlm.nih.gov/pubmed/19155274
http://dx.doi.org/10.1093/nar/gkn1086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655680/
https://www.ncbi.nlm.nih.gov/pubmed/19155274
http://dx.doi.org/10.1093/nar/gkn1086

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