How binding of small molecule and peptide ligands to HIV-1 TAR alters the RNA motional landscape

The HIV-1 TAR RNA represents a well-known paradigm to study the role of dynamics and conformational change in RNA function. This regulatory RNA changes conformation in response to binding of Tat protein and of a variety of peptidic and small molecule ligands, indicating that its conformational flexi...

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Detalles Bibliográficos
Autores principales: Bardaro, Michael F., Shajani, Zahra, Patora-Komisarska, Krystyna, Robinson, John A., Varani, Gabriele
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655691/
https://www.ncbi.nlm.nih.gov/pubmed/19139066
http://dx.doi.org/10.1093/nar/gkn1074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655691/
https://www.ncbi.nlm.nih.gov/pubmed/19139066
http://dx.doi.org/10.1093/nar/gkn1074

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