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How binding of small molecule and peptide ligands to HIV-1 TAR alters the RNA motional landscape
The HIV-1 TAR RNA represents a well-known paradigm to study the role of dynamics and conformational change in RNA function. This regulatory RNA changes conformation in response to binding of Tat protein and of a variety of peptidic and small molecule ligands, indicating that its conformational flexi...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655691/ https://www.ncbi.nlm.nih.gov/pubmed/19139066 http://dx.doi.org/10.1093/nar/gkn1074 |