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Regulator of G-Protein Signaling 14 (RGS14) Is a Selective H-Ras Effector

BACKGROUND: Regulator of G-protein signaling (RGS) proteins have been well-described as accelerators of Gα-mediated GTP hydrolysis (“GTPase-accelerating proteins” or GAPs). However, RGS proteins with complex domain architectures are now known to regulate much more than Gα GTPase activity. RGS14 cont...

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Detalles Bibliográficos
Autores principales: Willard, Francis S., Willard, Melinda D., Kimple, Adam J., Soundararajan, Meera, Oestreich, Emily A., Li, Xiaoyan, Sowa, Nathaniel A., Kimple, Randall J., Doyle, Declan A., Der, Channing J., Zylka, Mark J., Snider, William D., Siderovski, David P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655719/
https://www.ncbi.nlm.nih.gov/pubmed/19319189
http://dx.doi.org/10.1371/journal.pone.0004884