Selective Down-Regulation of Nuclear Poly(ADP-Ribose) Glycohydrolase

BACKGROUND: The formation of ADP-ribose polymers on target proteins by poly(ADP-ribose) polymerases serves a variety of cell signaling functions. In addition, extensive activation of poly(ADP-ribose) polymerase-1 (PARP-1) is a dominant cause of cell death in ischemia-reperfusion, trauma, and other c...

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Detalles Bibliográficos
Autores principales: Burns, David M., Ying, Weihai, Kauppinen, Tiina M., Zhu, Keqing, Swanson, Raymond A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655720/
https://www.ncbi.nlm.nih.gov/pubmed/19319190
http://dx.doi.org/10.1371/journal.pone.0004896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655720/
https://www.ncbi.nlm.nih.gov/pubmed/19319190
http://dx.doi.org/10.1371/journal.pone.0004896

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