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Regulatory T cells in systemic lupus erythematosus: past, present and future

Regulatory/suppressor T cells (Tregs) maintain immunologic homeo-stasis and prevent autoimmunity. In this article, past studies and recent studies of Tregs in mouse models for lupus and of human systemic lupus erythematosus are reviewed concentrating on CD4(+)CD25(+)Foxp3(+ )Tregs. These cells consi...

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Detalles Bibliográficos
Autor principal: Horwitz, David A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656253/
https://www.ncbi.nlm.nih.gov/pubmed/19040771
http://dx.doi.org/10.1186/ar2511