Cargando…

Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells

BACKGROUND: D-ribose in cells and human serum participates in glycation of proteins resulting in advanced glycation end products (AGEs) that affect cell metabolism and induce cell death. However, the mechanism by which D-ribose-glycated proteins induce cell death is still unclear. RESULTS: Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Yan, Chen, Lan, Chen, Ji, Ge, Lin, He, Rong Qiao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656460/
https://www.ncbi.nlm.nih.gov/pubmed/19216769
http://dx.doi.org/10.1186/1471-2121-10-10