Low frequency of CD4(+)CD25(+ )Treg in SLE patients: a heritable trait associated with CTLA4 and TGFβ gene variants

BACKGROUND: CD4(+)CD25(+ )regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE),...

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Detalles Bibliográficos
Autores principales: Barreto, Marta, Ferreira, Ricardo C, Lourenço, Lara, Moraes-Fontes, Maria F, Santos, Eugénia, Alves, Miguel, Carvalho, Cláudia, Martins, Berta, Andreia, Rita, Viana, João F, Vasconcelos, Carlos, Mota-Vieira, Luísa, Ferreira, Carlos, Demengeot, Jocelyne, Vicente, Astrid M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656467/
https://www.ncbi.nlm.nih.gov/pubmed/19173720
http://dx.doi.org/10.1186/1471-2172-10-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656467/
https://www.ncbi.nlm.nih.gov/pubmed/19173720
http://dx.doi.org/10.1186/1471-2172-10-5

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