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Brain-derived neurotrophic factor modulation of Kv1.3 channel is disregulated by adaptor proteins Grb10 and nShc

BACKGROUND: Neurotrophins are important regulators of growth and regeneration, and acutely, they can modulate the activity of voltage-gated ion channels. Previously we have shown that acute brain-derived neurotrophic factor (BDNF) activation of neurotrophin receptor tyrosine kinase B (TrkB) suppress...

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Detalles Bibliográficos
Autores principales: Colley, Beverly S, Cavallin, Melissa A, Biju, KC, Marks, David R, Fadool, Debra A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656512/
https://www.ncbi.nlm.nih.gov/pubmed/19166614
http://dx.doi.org/10.1186/1471-2202-10-8