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The glycine brace: a component of Rab, Rho, and Ran GTPases associated with hinge regions of guanine- and phosphate-binding loops

BACKGROUND: Ras-like GTPases function as on-off switches in intracellular signalling pathways and include the Rab, Rho/Rac, Ran, Ras, Arf, Sar and Gα families. How these families have evolutionarily diverged from each other at the sequence level provides clues to underlying mechanisms associated wit...

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Detalles Bibliográficos
Autor principal: Neuwald, Andrew F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656535/
https://www.ncbi.nlm.nih.gov/pubmed/19265520
http://dx.doi.org/10.1186/1472-6807-9-11