κ-Opioid System Regulates the Long-Lasting Behavioral Adaptations Induced by Early-Life Exposure to Methylphenidate

Methylphenidate (MPH) is commonly prescribed in childhood and adolescence for the treatment of attention–deficit/hyperactivity disorders. In rodents, MPH exposure during preadolescence (postnatal days [PD] 20–35) causes decreased sensitivity to drug and natural rewards, while enhancing a negative em...

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Detalles Bibliográficos
Autores principales: Wiley, Matthew D., Poveromo, Laura B., Antapasis, John, Herrera, Carolina M., Bolaños-Guzmán, Carlos A.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656574/
https://www.ncbi.nlm.nih.gov/pubmed/18923399
http://dx.doi.org/10.1038/npp.2008.188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656574/
https://www.ncbi.nlm.nih.gov/pubmed/18923399
http://dx.doi.org/10.1038/npp.2008.188

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