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κ-Opioid System Regulates the Long-Lasting Behavioral Adaptations Induced by Early-Life Exposure to Methylphenidate
Methylphenidate (MPH) is commonly prescribed in childhood and adolescence for the treatment of attention–deficit/hyperactivity disorders. In rodents, MPH exposure during preadolescence (postnatal days [PD] 20–35) causes decreased sensitivity to drug and natural rewards, while enhancing a negative em...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656574/ https://www.ncbi.nlm.nih.gov/pubmed/18923399 http://dx.doi.org/10.1038/npp.2008.188 |