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Adiponectin Haploinsufficiency Promotes Mammary Tumor Development in MMTV-PyVT Mice by Modulation of Phosphatase and Tensin Homolog Activities

BACKGROUND: Adiponectin is an adipokine possessing beneficial effects on obesity-related medical complications. A negative association of adiponectin levels with breast cancer development has been demonstrated. However, the precise role of adiponectin deficiency in mammary carcinogenesis remains elu...

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Detalles Bibliográficos
Autores principales: Lam, Janice B. B., Chow, Kim H. M., Xu, Aimin, Lam, Karen S. L., Liu, Jing, Wong, Nai-Sum, Moon, Randall T., Shepherd, Peter R., Cooper, Garth J. S., Wang, Yu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656613/
https://www.ncbi.nlm.nih.gov/pubmed/19319191
http://dx.doi.org/10.1371/journal.pone.0004968