Inhibition of Atrogin-1/MAFbx Mediated MyoD Proteolysis Prevents Skeletal Muscle Atrophy In Vivo

Ubiquitin ligase Atrogin1/Muscle Atrophy F-box (MAFbx) up-regulation is required for skeletal muscle atrophy but substrates and function during the atrophic process are poorly known. The transcription factor MyoD controls myogenic stem cell function and differentiation, and seems necessary to mainta...

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Detalles Bibliográficos
Autores principales: Lagirand-Cantaloube, Julie, Cornille, Karen, Csibi, Alfredo, Batonnet-Pichon, Sabrina, Leibovitch, Marie Pierre, Leibovitch, Serge A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656614/
https://www.ncbi.nlm.nih.gov/pubmed/19319192
http://dx.doi.org/10.1371/journal.pone.0004973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656614/
https://www.ncbi.nlm.nih.gov/pubmed/19319192
http://dx.doi.org/10.1371/journal.pone.0004973

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