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HIV Aspartyl Peptidase Inhibitors Interfere with Cellular Proliferation, Ultrastructure and Macrophage Infection of Leishmania amazonensis

BACKGROUND: Leishmania is the etiologic agent of leishmanisais, a protozoan disease whose pathogenic events are not well understood. Current therapy is suboptimal due to toxicity of the available therapeutic agents and the emergence of drug resistance. Compounding these problems is the increase in t...

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Detalles Bibliográficos
Autores principales: Santos, Lívia O., Marinho, Fernanda A., Altoé, Ellen F., Vitório, Bianca S., Alves, Carlos R., Britto, Constança, Motta, Maria Cristina M., Branquinha, Marta H., Santos, André L. S., d'Avila-Levy, Claudia M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656615/
https://www.ncbi.nlm.nih.gov/pubmed/19325703
http://dx.doi.org/10.1371/journal.pone.0004918