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Higher expression of deoxyuridine triphosphatase (dUTPase) may predict the metastasis potential of colorectal cancer

AIMS: 5-Fluorouracil (5-FU) is one of the most widely used anticancer drugs; however, the activity of 5-FU is determined by the presence of several enzymes that limit its activation or degradation, and these include dihydropyrimidine dehydrogenase (DPD), orotate phosphoribosyl transferase (OPRT), th...

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Detalles Bibliográficos
Autores principales: Kawahara, A, Akagi, Y, Hattori, S, Mizobe, T, Shirouzu, K, Ono, M, Yanagawa, T, Kuwano, M, Kage, M
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656677/
https://www.ncbi.nlm.nih.gov/pubmed/19052026
http://dx.doi.org/10.1136/jcp.2008.060004