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Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation

INTRODUCTION: The prolactin-Janus-kinase-2-signal transducer and activator of transcription-5 (JAK2-STAT5) pathway is essential for the development and functional differentiation of the mammary gland. The pathway also has important roles in mammary tumourigenesis. Prolactin regulated target genes ar...

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Detalles Bibliográficos
Autores principales: Perotti, Christian, Liu, Ruixuan, Parusel, Christine T, Böcher, Nadine, Schultz, Jörg, Bork, Peer, Pfitzner, Edith, Groner, Bernd, Shemanko, Carrie S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656886/
https://www.ncbi.nlm.nih.gov/pubmed/19014541
http://dx.doi.org/10.1186/bcr2193