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A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species

We have mapped a protein interaction network of human homologs of proteins that modify longevity in invertebrate species. This network is derived from a proteome-scale human protein interaction Core Network generated through unbiased high-throughput yeast two-hybrid searches. The longevity network i...

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Detalles Bibliográficos
Autores principales: Bell, Russell, Hubbard, Alan, Chettier, Rakesh, Chen, Di, Miller, John P., Kapahi, Pankaj, Tarnopolsky, Mark, Sahasrabuhde, Sudhir, Melov, Simon, Hughes, Robert E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657003/
https://www.ncbi.nlm.nih.gov/pubmed/19293945
http://dx.doi.org/10.1371/journal.pgen.1000414