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Alignment and Prediction of cis-Regulatory Modules Based on a Probabilistic Model of Evolution

Cross-species comparison has emerged as a powerful paradigm for predicting cis-regulatory modules (CRMs) and understanding their evolution. The comparison requires reliable sequence alignment, which remains a challenging task for less conserved noncoding sequences. Furthermore, the existing models o...

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Detalles Bibliográficos
Autores principales: He, Xin, Ling, Xu, Sinha, Saurabh
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657044/
https://www.ncbi.nlm.nih.gov/pubmed/19293946
http://dx.doi.org/10.1371/journal.pcbi.1000299