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Alignment and Prediction of cis-Regulatory Modules Based on a Probabilistic Model of Evolution
Cross-species comparison has emerged as a powerful paradigm for predicting cis-regulatory modules (CRMs) and understanding their evolution. The comparison requires reliable sequence alignment, which remains a challenging task for less conserved noncoding sequences. Furthermore, the existing models o...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657044/ https://www.ncbi.nlm.nih.gov/pubmed/19293946 http://dx.doi.org/10.1371/journal.pcbi.1000299 |