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Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy

In eukaryotic cells, control mechanisms have developed that restrain cell-cycle transitions in response to stress. These regulatory pathways are termed cell-cycle checkpoints. The G(2)/M checkpoint prevents cells from entering mitosis when DNA is damaged in order to afford these cells an opportunity...

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Detalles Bibliográficos
Autores principales: Wang, Yingmei, Ji, Ping, Liu, Jinsong, Broaddus, Russell R, Xue, Fengxia, Zhang, Wei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657106/
https://www.ncbi.nlm.nih.gov/pubmed/19216791
http://dx.doi.org/10.1186/1476-4598-8-8