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Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer

BACKGROUND: Carboxypeptidase 4 (CPA4) is a zinc-dependent metallocarboxypeptidase on chromosome 7q32 in a region linked to prostate cancer aggressiveness. CPA4 is involved in the histone hyperacetylation pathway and may modulate the function of peptides that affect the growth and regulation of prost...

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Detalles Bibliográficos
Autores principales: Ross, Phillip L, Cheng, Iona, Liu, Xin, Cicek, Mine S, Carroll, Peter R, Casey, Graham, Witte, John S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657151/
https://www.ncbi.nlm.nih.gov/pubmed/19245716
http://dx.doi.org/10.1186/1471-2407-9-69