Design of Early Validation Trials of Biomarkers

The design of early-phase studies of putative screening markers in clinical populations is discussed. Biological, epidemiological, statistical and computational issues all affect the design of early-phase studies of these markers, but there are frequently little or no data in hand to facilitate the...

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Detalles Bibliográficos
Autores principales: Normolle, Daniel, Ruffin, Mack T., Brenner, Dean
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2007
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657653/
https://www.ncbi.nlm.nih.gov/pubmed/19305629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657653/
https://www.ncbi.nlm.nih.gov/pubmed/19305629

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