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Design of Early Validation Trials of Biomarkers
The design of early-phase studies of putative screening markers in clinical populations is discussed. Biological, epidemiological, statistical and computational issues all affect the design of early-phase studies of these markers, but there are frequently little or no data in hand to facilitate the...
Autores principales: | Normolle, Daniel, Ruffin, Mack T., Brenner, Dean |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657653/ https://www.ncbi.nlm.nih.gov/pubmed/19305629 |
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