Comparative genomics of aldehyde dehydrogenase 5a1 (succinate semialdehyde dehydrogenase) and accumulation of gamma-hydroxybutyrate associated with its deficiency

Succinic semialdehyde dehydrogenase (SSADH; aldehyde dehydrogenase 5A1 [ALDH5A1]; locus 6p22) occupies a central position in central nervous system (CNS) neurotransmitter metabolism as one of two enzymes necessary for γ-aminobutyric acid (GABA) recycling from the synaptic cleft. Its importance is hi...

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Detalles Bibliográficos
Autores principales: Malaspina, Patrizia, Picklo, Matthew J, Jakobs, C, Snead, O Carter, Gibson, K Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657722/
https://www.ncbi.nlm.nih.gov/pubmed/19164088
http://dx.doi.org/10.1186/1479-7364-3-2-106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657722/
https://www.ncbi.nlm.nih.gov/pubmed/19164088
http://dx.doi.org/10.1186/1479-7364-3-2-106

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