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A Drosophila systems model of pentylenetetrazole induced locomotor plasticity responsive to antiepileptic drugs

BACKGROUND: Rodent kindling induced by PTZ is a widely used model of epileptogenesis and AED testing. Overlapping pathophysiological mechanisms may underlie epileptogenesis and other neuropsychiatric conditions. Besides epilepsy, AEDs are widely used in treating various neuropsychiatric disorders. M...

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Detalles Bibliográficos
Autores principales: Mohammad, Farhan, Singh, Priyanka, Sharma, Abhay
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657775/
https://www.ncbi.nlm.nih.gov/pubmed/19154620
http://dx.doi.org/10.1186/1752-0509-3-11