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Cleavage of Armadillo/beta-catenin by the caspase DrICE in Drosophila apoptotic epithelial cells

BACKGROUND: During apoptosis cells become profoundly restructured through concerted cleavage of cellular proteins by caspases. In epithelial tissues, apoptotic cells loose their apical/basal polarity and are extruded from the epithelium. We used the Drosophila embryo as a system to investigate the r...

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Detalles Bibliográficos
Autores principales: Kessler, Thomas, Müller, H Arno J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657781/
https://www.ncbi.nlm.nih.gov/pubmed/19232093
http://dx.doi.org/10.1186/1471-213X-9-15