Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21)

The involvement of complement receptor 2 (CR2) in B cell tolerance and autoimmune disease has been revealed over the past decade or so. Our previous studies have established that mice prematurely expressing human CR2 under the control of a lambda light chain promoter (in particular the hCR2(high) li...

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Detalles Bibliográficos
Autores principales: Pappworth, Isabel Y., Kulik, Liudmila, Haluszczak, Catherine, Reuter, Jason W., Holers, V. Michael, Marchbank, Kevin J.
Formato: Texto
Lenguaje:English
Publicado: Pergamon Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657831/
https://www.ncbi.nlm.nih.gov/pubmed/19187965
http://dx.doi.org/10.1016/j.molimm.2008.08.273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657831/
https://www.ncbi.nlm.nih.gov/pubmed/19187965
http://dx.doi.org/10.1016/j.molimm.2008.08.273

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