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ER stress affects processing of MHC class I-associated peptides

BACKGROUND: Viral infection and neoplastic transformation trigger endoplasmic reticulum (ER) stress. Thus, a large proportion of the cells that must be recognized by the immune system are stressed cells. Cells respond to ER stress by launching the unfolded protein response (UPR). The UPR regulates t...

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Detalles Bibliográficos
Autores principales: Granados, Diana P, Tanguay, Pierre-Luc, Hardy, Marie-Pierre, Caron, Étienne, de Verteuil, Danielle, Meloche, Sylvain, Perreault, Claude
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657905/
https://www.ncbi.nlm.nih.gov/pubmed/19220912
http://dx.doi.org/10.1186/1471-2172-10-10