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Expression profiling and Ingenuity biological function analyses of interleukin-6- versus nerve growth factor-stimulated PC12 cells

BACKGROUND: The major goal of the study was to compare the genetic programs utilized by the neuropoietic cytokine Interleukin-6 (IL-6) and the neurotrophin (NT) Nerve Growth Factor (NGF) for neuronal differentiation. RESULTS: The designer cytokine Hyper-IL-6 in which IL-6 is covalently linked to its...

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Detalles Bibliográficos
Autores principales: Kunz, Dieter, Walker, Gaby, Bedoucha, Marc, Certa, Ulrich, März-Weiss, Pia, Dimitriades-Schmutz, Beatrice, Otten, Uwe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657914/
https://www.ncbi.nlm.nih.gov/pubmed/19239705
http://dx.doi.org/10.1186/1471-2164-10-90